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Home - Products - Chromatin/Epigenetic - Epigenetic Reader Domain - SMARCA-BD ligand 1 for Protac dihydrochloride

SMARCA-BD ligand 1 for Protac dihydrochloride

CAS No. 2369053-68-7

SMARCA-BD ligand 1 for Protac dihydrochloride( —— )

Catalog No. M33234 CAS No. 2369053-68-7

SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunit SMARCA2 and is used for degrading SMARCA2 based on PROTAC.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SMARCA-BD ligand 1 for Protac dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunit SMARCA2 and is used for degrading SMARCA2 based on PROTAC.
  • Description
    SMARCA-BD ligand 1 for Protac dihydrochloride is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Epigenetic Reader Domain
  • Recptor
    Epigenetic Reader Domain
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2369053-68-7
  • Formula Weight
    344.24
  • Molecular Formula
    C14H19Cl2N5O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 2.7 mg/mL (7.84 mM; Ultrasonic (<60°C)
  • SMILES
    Cl.Cl.Nc1nnc(cc1N1CCNCC1)-c1ccccc1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.?
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